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Natamycin 7681-93-8

Natamycin 7681-93-8

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product description
ItemDescription
Product NameNatamycin (Pimaricin)
CAS No.7681-93-8
EINECS No.231-683-5
Molecular FormulaC₃₃H₄₇NO₁₃
Molecular Weight665.73
AppearanceOff-white to cream-yellow crystalline powder, almost odorless and tasteless
SourceProduced by controlled fermentation of Streptomyces natalensis
Main GradesFood Grade (meets GB 2760, FCC, JECFA); Pharmaceutical Grade (for topical antifungal treatment); Reagent/High Purity Grade (≥98%, for laboratory use)
Key Physical & Chemical PropertiesAppearance: Off-white to cream-yellow crystalline powder, almost odorless and tasteless; Melting Point: approx. 280℃ (decomposes); Solubility: Slightly soluble in water (0.41g/L at 21℃), slightly soluble in methanol, soluble in glacial acetic acid and DMSO, insoluble in most organic solvents; pH Stability: Solubility increases above pH 9 or below pH 3, stable in most food pH ranges; Photosensitivity: Sensitive to UV light, avoid sunlight exposure; Thermal Stability: Relatively stable in dry state, withstands short-term high temperature (100℃)
Mechanism of ActionA polyene macrolide antifungal antibiotic. Acts by specifically binding to ergosterol in fungal cell membranes, blocking transmembrane transport of amino acids and glucose, inhibiting fungal growth. Unlike nystatin and filipin, natamycin does not alter membrane permeability.
FeaturesNatural origin, produced by fermentation; broad-spectrum antifungal activity against molds and yeasts; highly effective at low concentrations (1/50-1/100 of potassium sorbate); colorless and tasteless, does not affect food flavor; low risk of microbial resistance; poorly absorbed by human body, high safety profile; inhibits mycotoxin production
Main ApplicationsFood Industry: Natural antifungal preservative (E235/INS 235). Used in cheese (max 0.3g/kg, surface treatment), pastries/mooncakes (0.3g/kg), meat products (0.3g/kg), fermented wine (0.01g/L), fruit/vegetable juice (0.3g/kg), mayonnaise/dressing (0.02g/kg). Residual amount <10mg/kg; Pharmaceutical: Treatment of fungal keratitis, effective against Candida, Aspergillus, Fusarium, etc.; Others: Feed preservative, cultural heritage protection, agricultural product preservation
PackagingStandard: 100g/bottle, 500g/bottle, 1kg/bag, 5kg/bag, 25kg/drum; custom packaging available
Storage ConditionsStore at 2-8℃, protected from light, in sealed containers; avoid contact with oxidizers and sulfhydryl compounds; store in cool, dry, sealed conditions
Shipping RequirementsNon-hazardous cargo; protect from light, moisture, and high temperature during transport; handle with care
Quality StandardsFood Grade: GB 25532, GB 2760-2024, FCC, FAO/WHO JECFA, FDA 21 CFR 172.155, EU E235; Assay: Food grade ≥95%, High purity ≥98%, Pharma 97.0%-102.0% (dry basis); Heavy Metals ≤10ppm; Lead ≤2mg/kg; Moisture ≤9%; pH (1% solution): 5.0-7.5
Minimum Order QuantityStandard 1kg; sample orders available (100g/500g)
Delivery TimeStandard 7-15 working days
Payment TermsT/T (30% deposit, 70% against B/L copy); FOB/CFR/CIF supported
HS Code29419090 (Other antibiotics)


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FAQ

1. What are Jinyu Chemical primary product lines?
Our company specializes in petrochemicals (methanol, styrene, ethylene glycol), plastic resins (PP, PE, PVC, ABS), fine chemicals (pharmaceutical/pesticide intermediates, additives, solvents), chemical fiber raw materials (PTA, polyester filament, polyester staple fiber), inorganic chemicals (soda ash, caustic soda, titanium dioxide), as well as rubber, paraffin wax, and other products. We offer one-stop procurement services covering a wide range of categories.


2. Are you a trading company or a manufacturer?
We are a professional chemical trading company specializing in international trade. We have established long-term strategic partnerships with numerous high-quality domestic manufacturers to ensure a stable supply of goods and competitive pricing, while also providing comprehensive export services throughout the entire process.


3. Can you provide third-party inspection reports?
Yes. We provide a Certificate of Analysis (COA) with every shipment. Additionally, upon a client's request, we can arrange for inspections by third-party agencies such as SGS, BV, or ITS; the associated costs and details are negotiable.


4. What is the Minimum Order Quantity (MOQ)?
For plastic resins and chemical fiber raw materials, the MOQ typically starts at 1–5 tons, and we welcome small-batch trial orders. For liquid chemicals, bulk shipments start at 20 tons, while drummed shipments can be consolidated (LCL). For fine chemicals, the MOQ is determined on a case-by-case basis depending on the specific product.


5. From which ports do you primarily ship?
Our company is located in close proximity to the Port of Tianjin. We can also arrange shipments from other major domestic ports—such as Qingdao or Shanghai—to meet our clients' specific requirements.


6. Can you handle the export of hazardous materials?
Yes. Our company holds a valid license for the operation of hazardous chemicals. We are well-versed in the procedures for hazardous material declaration, obtaining hazardous packaging certificates, and booking cargo space, thereby ensuring full compliance with all export regulations.


7. What payment methods do you accept?
Our standard payment terms are T/T (30% upfront deposit, with the remaining 70% payable upon presentation of a copy of the Bill of Lading) or Sight L/C (Letter of Credit). For small-batch sample orders, we also accept Western Union. For long-term partners—subject to a credit assessment—we may negotiate deferred L/C or Open Account (OA) terms.


8. What is your typical lead time?
For standard products, the lead time is typically 7–15 business days. For customized products or those with special specifications, it is 15–25 business days. For in-stock items, shipments can be dispatched within 3–7 business days after receipt of payment.

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